Well, for one, their brains are made to handle extra limbs. A human's can only handle four. S'why we don't have tails.

[Though, that wasn't all that helpful, really, unless Hiro decided to change his brain to a squid-brain, but then he suspected his transformation into the Giant Alien Squid From Beyond The Stars would be complete, and Hiro would cease to exist. Hm. Which one would he prefer...]

But, maybe you'll get used to it eventually. Hell, you might have to. I mean, who knows how long you'll be stuck like that. It might be days, or weeks... maybe months... years...